Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175858 | 0.92 | AKR1C3 (0.58) | AKR1C3GAAALPLCA9MAPT | |
| SCHEMBL13175905 | 0.90 | AKR1C3 (0.56) | AKR1C3GAAALPLMAPTKDM5B | |
| SCHEMBL13175870 | 0.89 | AKR1C3 (0.56) | AKR1C3GAAALPLKDM5B | |
| SCHEMBL13175906 | 0.88 | AKR1C3 (0.56) | AKR1C3GAAALPLMAPTKDM5B | |
| SCHEMBL13175632 | 0.87 | AKR1C3 (0.59) | AKR1C3ALPLMAPTKDM5B | |
| SCHEMBL13175641 | 0.86 | AKR1C3 (0.53) | AKR1C3GAAALPLKDM5B | |
| SCHEMBL13175614 | 0.86 | AKR1C3 (0.62) | AKR1C3MAPTKDM5B | |
| SCHEMBL13175601 | 0.86 | AKR1C3 (0.58) | AKR1C3GAAALPLMAPTKDM5B | |
| SCHEMBL13175900 | 0.84 | AKR1C3 (0.56) | AKR1C3MAPTKDM5B | |
| SCHEMBL13175737 | 0.82 | AKR1C3 (0.58) | AKR1C3ALPLKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |