Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210409 | 1.00 | TSHR (0.53) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL16817197 | 1.00 | TSHR (0.53) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL13210319 | 1.00 | TSHR (0.53) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL4831130 | 1.00 | TSHR (0.53) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL13177044 | 0.87 | TSHR (0.42) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL13176829 | 0.87 | TSHR (0.42) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL14004276 | 0.87 | TSHR (0.42) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL13176731 | 0.87 | TSHR (0.42) | TSHRTRPA1ALDH1A1LMNATDP1 | |
| SCHEMBL4396539 | 0.86 | — | — | |
| SCHEMBL2230756 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |