Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800544 | 0.90 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL1800537 | 0.90 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL12350092 | 0.84 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL1793824 | 0.83 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1793828 | 0.83 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1801723 | 0.82 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL1801720 | 0.82 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL1802379 | 0.81 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1802382 | 0.81 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1796863 | 0.80 | TRPV1 (0.70) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021330-B1 | BENZIMIDAZOLE MODULATORS OF VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-22 | — | — | EP | disclosed |