Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925099 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1ATMMAPTMEN1 | |
| SCHEMBL2925095 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1ATMMAPTMEN1 | |
| SCHEMBL2923647 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1ATMMAPTMEN1 | |
| SCHEMBL2928051 | 0.83 | MCHR1 (0.59) | NPC1RAB9AMCHR1HTR2CPABPC1 | |
| SCHEMBL2925595 | 0.83 | MCHR1 (0.59) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL2926363 | 0.82 | MCHR1 (0.58) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13177410 | 0.82 | MCHR1 (0.58) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2925938 | 0.82 | MCHR1 (0.72) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2926846 | 0.81 | MCHR1 (0.65) | KDM4EALDH1A1ATMMAPTMEN1 | |
| SCHEMBL2921082 | 0.81 | MCHR1 (0.60) | KDM4EALDH1A1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285651-B1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2010-09-01 | — | — | EP | disclosed |