Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108126 | 0.78 | GALR1 (0.35) | GALR1HCAR2KDM4E | |
| SCHEMBL2108531 | 0.78 | HCAR2 (0.36) | GALR1SLC9A1DHODHHCAR2ALDH1A1 | |
| SCHEMBL2619818 | 0.77 | GALR1 (0.34) | GALR1DHODHHCAR2ALDH1A1 | |
| SCHEMBL2108726 | 0.77 | HCAR2 (0.38) | GALR1SLC9A1DHODHHCAR2ALDH1A1 | |
| SCHEMBL2108564 | 0.75 | GALR1 (0.35) | GALR1DHODHKDM4EMAPT | |
| SCHEMBL2108548 | 0.75 | MAPT (0.36) | GALR1DHODHHCAR2ALDH1A1KDM4E | |
| SCHEMBL21346644 | 0.75 | NISCH (0.35) | GALR1DHODHALDH1A1KDM4EMAPT | |
| SCHEMBL13177462 | 0.71 | SMN1; SMN2 (0.39) | DHODHHCAR2ALDH1A1KDM4EMAPT | |
| SCHEMBL2619798 | 0.69 | IDO1 (0.44) | ALDH1A1 | |
| SCHEMBL2619819 | 0.68 | IDO1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233474-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |