Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 20/20 | 0.58 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917672 | 0.87 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL917671 | 0.87 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL3240615 | 0.77 | GALR3 (0.87) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL918247 | 0.77 | GALR3 (0.87) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5359948 | 0.74 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5359954 | 0.74 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL916932 | 0.74 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL918241 | 0.74 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL918243 | 0.74 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL916933 | 0.74 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957067-B1 | INDOLONE COMPOUNDS USEFUL TO TREAT COGNITIVE IMPAIRMENT | HELICON THERAPEUTICS INC (US) | 2010-09-08 | — | — | EP | disclosed |