Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13178110 | 0.91 | TTK (0.56) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL13178065 | 0.89 | TTK (0.62) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL4767745 | 0.87 | TTK (0.66) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL13178112 | 0.85 | TTK (0.55) | TTK | |
| SCHEMBL3700229 | 0.82 | TTK (0.69) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3700563 | 0.81 | TTK (0.63) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3253947 | 0.80 | TTK (0.68) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL4767536 | 0.80 | TTK (0.60) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3708381 | 0.79 | TTK (0.65) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL3702420 | 0.79 | TTK (0.69) | TTKPIK3CBMAPK8PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |