Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 17/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ulodesine SCHEMBL4736609 | 0.88 | PNP (1.00) | PNP | |
| Ulodesine SCHEMBL12715509 | 0.88 | PNP (1.00) | PNP | |
| Ulodesine SCHEMBL13606448 | 0.88 | PNP (1.00) | PNP | |
| Ulodesine SCHEMBL474735 | 0.88 | PNP (1.00) | PNP | |
| SCHEMBL15315689 | 0.87 | PNP (0.81) | PNP | |
| SCHEMBL9888172 | 0.87 | PNP (0.81) | PNP | |
| SCHEMBL9888126 | 0.85 | PNP (0.78) | PNP | |
| SCHEMBL15315687 | 0.85 | PNP (0.78) | PNP | |
| SCHEMBL9888032 | 0.85 | PNP (0.82) | PNP | |
| SCHEMBL15318135 | 0.85 | PNP (0.78) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111381-A2 | USEFUL PHARMACEUTICAL SALTS OF 7-[(3R, 4R)-3-HYDROXY-4-HYDROXYMETHYL-PYRROLIDIN-1-YLMETHYL]-3,5-DIHYDRO-PYRROLO[3,2-D]PYRIMIDIN-4-ONE | BIOCRYST PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |