Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040816 | 1.00 | MME (0.43) | MMEPIK3CDBRD4POLBMAPT | |
| SCHEMBL2931296 | 1.00 | MME (0.43) | MMEPIK3CDBRD4POLBMAPT | |
| SCHEMBL12418611 | 0.83 | MME (0.36) | MMEPIK3CDBRD4POLBMAPT | |
| SCHEMBL17532408 | 0.79 | PIK3CD (0.35) | MMEPIK3CD | |
| SCHEMBL11912104 | 0.78 | MAPT (0.41) | MMEPIK3CDMAPT | |
| SCHEMBL13802677 | 0.78 | MAPT (0.41) | MMEPIK3CDMAPT | |
| SCHEMBL18570060 | 0.77 | MME (0.35) | MME | |
| SCHEMBL24342080 | 0.76 | MME (0.31) | MMEPIK3CD | |
| SCHEMBL21153268 | 0.75 | MME (0.33) | MMEPIK3CDMAPT | |
| SCHEMBL13558663 | 0.74 | MAPT (0.34) | MMEPIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501819-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-09-15 | — | — | EP | disclosed |