Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084964 | 0.92 | MC4R (0.62) | MC4R | |
| SCHEMBL13725362 | 0.78 | MC4R (0.51) | MC4R | |
| SCHEMBL3088366 | 0.76 | MC4R (0.63) | MC4R | |
| SCHEMBL13147026 | 0.76 | MC4R (0.66) | MC4R | |
| SCHEMBL3084971 | 0.75 | MC4R (0.71) | MC4R | |
| SCHEMBL3089431 | 0.74 | MC4R (0.71) | MC4R | |
| SCHEMBL13147034 | 0.74 | MC4R (0.66) | MC4R | |
| SCHEMBL13724049 | 0.73 | MC4R (0.48) | MC4R | |
| SCHEMBL3090271 | 0.73 | MC4R (0.72) | MC4R | |
| SCHEMBL13723344 | 0.72 | MC4R (0.49) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790719-B2 | Modulators of melanocortin receptor | ORE PHARMACEUTICALS, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |