⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18204079 | 0.79 | — | — | |
| SCHEMBL22858679 | 0.79 | — | — | |
| SCHEMBL8504951 | 0.78 | — | — | |
| SCHEMBL23732767 | 0.77 | — | — | |
| SCHEMBL21592908 | 0.77 | — | — | |
| SCHEMBL18685936 | 0.75 | CACNA2D1 (0.37) | — | |
| SCHEMBL24723652 | 0.75 | — | — | |
| SCHEMBL26424566 | 0.73 | — | — | |
| SCHEMBL92497 | 0.71 | — | — | |
| SCHEMBL18696893 | 0.71 | CYP1A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196376-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170334882-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC | 2017-11-23 | — | — | US | disclosed |
| US-20100234334-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2010-09-16 | — | — | US | disclosed |
| US-20100093685-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. | 2010-04-15 | — | — | US | disclosed |
| US-20100041633-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2010-02-18 | — | — | US | disclosed |
| WO-2008095809-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008095806-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008095808-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |