Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10175828 | 0.91 | MEN1 (0.77) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL2610129 | 0.88 | MEN1 (0.70) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL13182091 | 0.86 | MEN1 (0.78) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL2610054 | 0.86 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL13182088 | 0.85 | MEN1 (0.80) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL2610179 | 0.84 | MEN1 (0.82) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL2607539 | 0.84 | MEN1 (0.78) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL13182090 | 0.83 | MEN1 (0.80) | MEN1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL13182214 | 0.83 | MEN1 (0.94) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL2610125 | 0.83 | MEN1 (0.71) | MEN1KMT2AKDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108187-A2 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2010-09-23 | — | — | WO | disclosed |