Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005794 | 1.00 | IDH1 (0.91) | IDH1HSD11B1 | |
| SCHEMBL2005793 | 1.00 | IDH1 (0.91) | IDH1HSD11B1 | |
| SCHEMBL2004709 | 0.99 | IDH1 (0.93) | IDH1HSD11B1 | |
| SCHEMBL2008275 | 0.99 | IDH1 (0.93) | IDH1HSD11B1 | |
| SCHEMBL13182599 | 0.99 | IDH1 (0.93) | IDH1HSD11B1 | |
| SCHEMBL13599991 | 0.96 | IDH1 (0.98) | IDH1HSD11B1 | |
| SCHEMBL4453896 | 0.96 | IDH1 (0.98) | IDH1HSD11B1 | |
| SCHEMBL1970745 | 0.96 | IDH1 (0.98) | IDH1HSD11B1 | |
| SCHEMBL12571200 | 0.96 | IDH1 (0.98) | IDH1HSD11B1 | |
| SCHEMBL2009075 | 0.96 | IDH1 (0.98) | IDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233480-A1 | Chemical compounds | AstraZeneca AB (SE) | 2010-09-29 | — | — | EP | disclosed |