Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25863316 | 0.94 | MAPT (0.78) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL9152761 | 0.92 | MAPT (0.81) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9967348 | 0.91 | MAPT (0.58) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL12337501 | 0.89 | MAPT (0.71) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL12451793 | 0.88 | MAPT (0.69) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL13161708 | 0.88 | MAPT (0.69) | MAPTTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL13184184 | 0.88 | MAPT (0.69) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL9967351 | 0.86 | MAPT (0.54) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL21942016 | 0.86 | ESR1 (0.67) | MAPTTDP1L3MBTL1ESR1ESR2 | |
| SCHEMBL8862933 | 0.86 | ESR1 (0.67) | MAPTTDP1L3MBTL1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803507-B2 | Electrophotographic photoreceptor and image forming apparatus including the same | SHARP KABUSHIKI KAISHA (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20070026334-A1 | Electrophotographic photoreceptor and image forming apparatus including the same | SHARP KABUSHIKI KAISHA (JP) | 2007-02-01 | — | — | US | disclosed |