Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132124 | 0.93 | CHRM3 (0.57) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL130786 | 0.88 | CHRM3 (0.59) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL132559 | 0.86 | CHRM3 (0.51) | CHRM3CHRM1CHRM2 | |
| SCHEMBL131856 | 0.83 | CHRM3 (0.47) | CHRM3CHRM1CHRM2LMNA | |
| SCHEMBL132922 | 0.80 | CHRM3 (0.62) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL99413 | 0.80 | CHRM3 (0.62) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL99414 | 0.80 | CHRM3 (0.62) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL130410 | 0.79 | CHRM3 (0.61) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL98781 | 0.79 | CHRM3 (0.61) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL98780 | 0.79 | CHRM3 (0.61) | CHRM3CHRM1CHRM2CHRM4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |