Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220060 | 0.91 | BTK (0.71) | BTK | |
| SCHEMBL3212026 | 0.90 | BTK (0.80) | BTK | |
| SCHEMBL3216274 | 0.89 | BTK (0.79) | BTK | |
| SCHEMBL3222693 | 0.89 | BTK (0.78) | BTK | |
| SCHEMBL1728752 | 0.88 | BTK (0.71) | BTK | |
| SCHEMBL3212541 | 0.88 | BTK (0.68) | BTK | |
| SCHEMBL3220381 | 0.88 | BTK (0.72) | BTK | |
| SCHEMBL3212901 | 0.88 | BTK (0.72) | BTK | |
| SCHEMBL3223351 | 0.88 | BTK (0.69) | BTK | |
| SCHEMBL3203373 | 0.88 | BTK (0.89) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100070-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-10 | — | — | WO | disclosed |