Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.56 |
| ▸ | NPY1R | P25929 | 9/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.56 |
| ▸ | NPY2R | P49146 | 5/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188046 | 1.00 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL10075166 | 0.98 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL2623540 | 0.96 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL2623546 | 0.96 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL10074914 | 0.93 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL13188059 | 0.92 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL2632331 | 0.91 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL2632424 | 0.91 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL2632373 | 0.91 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RKEAP1 | |
| SCHEMBL10074918 | 0.89 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010105367-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | VALORISATION-RECHERCHE SOCIETE EN COMMANDITE (CA) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010106441-A2 | PEPTIDOMIMETICS FOR MODULATING INTERLEUKIN-1 RECEPTOR | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2010-09-23 | — | — | WO | disclosed |