Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663770 | 0.86 | SMN1; SMN2 (0.90) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL29978651 | 0.86 | SMN1; SMN2 (0.90) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL662898 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL29978107 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL662004 | 0.83 | KMT2A (0.76) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL663209 | 0.83 | MAPT (0.90) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL29978203 | 0.83 | MAPT (0.90) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL21376548 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL21376835 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL666388 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101964-A2 | METHODS AND COMPOSITIONS USEFUL IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS, INC (US) | 2010-09-10 | — | — | WO | disclosed |