Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422923 | 1.00 | HSP90AA1 (0.70) | HSP90AA1 | |
| SCHEMBL422924 | 1.00 | HSP90AA1 (0.70) | HSP90AA1 | |
| SCHEMBL13190077 | 0.91 | HSP90AA1 (0.84) | HSP90AA1 | |
| SCHEMBL458828 | 0.91 | HSP90AA1 (0.84) | HSP90AA1 | |
| SCHEMBL458829 | 0.91 | HSP90AA1 (0.84) | HSP90AA1 | |
| SCHEMBL1394578 | 0.89 | HSP90AA1 (0.83) | HSP90AA1 | |
| SCHEMBL1394579 | 0.89 | HSP90AA1 (0.83) | HSP90AA1 | |
| SCHEMBL10215201 | 0.89 | HSP90AA1 (0.83) | HSP90AA1 | |
| SCHEMBL426916 | 0.89 | HSP90AA1 (0.69) | HSP90AA1 | |
| SCHEMBL426915 | 0.89 | HSP90AA1 (0.69) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106290-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | disclosed |