SCHEMBL13191024

SCHEMBL13191024

N#CCCC#Cc1ccc(-c2c(C#N)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.72
CNR2 P34972 18/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13191028 0.93 CNR1 (0.65) CNR1CNR2
SCHEMBL13191027 0.92 CNR1 (0.65) CNR1CNR2
SCHEMBL662270 0.91 CNR1 (0.87) CNR1CNR2
SCHEMBL13191017 0.90 CNR1 (0.89) CNR1CNR2
SCHEMBL4971108 0.86 CNR1 (0.76) CNR1CNR2
SCHEMBL660638 0.85 CNR1 (0.80) CNR1CNR2
SCHEMBL3750294 0.84 CNR1 (1.00) CNR1CNR2
SCHEMBL13191016 0.84 CNR1 (0.75) CNR1CNR2
SCHEMBL3740232 0.83 CNR1 (1.00) CNR1CNR2
SCHEMBL3752858 0.83 CNR1 (1.00) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853205-B2 Heteropyrrole analogs acting on cannabinoid receptors UNIVERSITY OF CONNECTICUT (US) 2014-10-07 US disclosed
WO-2010104488-A1 NOVEL HETERO PYRROLE ANALOGS ACTING ON CANNAPINOID RECEPTORS UNIVERSITY OF CONNECTICUT (US) 2010-09-16 WO disclosed