Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191868 | 1.00 | SPHK1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL13191873 | 1.00 | SPHK1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL13191918 | 1.00 | SPHK1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL13191871 | 1.00 | SPHK1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL13191877 | 1.00 | SPHK1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL13191915 | 1.00 | SPHK1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL7614461 | 0.88 | S1PR1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL7620506 | 0.88 | S1PR1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| SCHEMBL7614453 | 0.88 | S1PR1 (0.68) | SPHK1S1PR1S1PR2ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL7616910 | 0.86 | S1PR1 (0.66) | SPHK1S1PR1S1PR2ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012136121-A1 | AMINO PHENYLPROPANOID COMPOUND AND USE THEREOF FOR PREPARING IMMUNOSUPPRESSANT | 中国人民解放军军事医学科学院毒物药物研究所 (CN) | 2012-10-11 | — | — | WO | disclosed |