Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587258 | 0.90 | HTR2C (0.51) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30065232 | 0.86 | SMN1; SMN2 (0.51) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL928649 | 0.86 | HTR2C (0.50) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22537068 | 0.79 | HTR2C (0.53) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3335937 | 0.77 | SMN1; SMN2 (0.52) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL286830 | 0.77 | HTR2C (0.51) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15409979 | 0.77 | HTR2C (0.51) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1795685 | 0.77 | SMN1; SMN2 (0.52) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3822619 | 0.77 | SMN1; SMN2 (0.52) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5517077 | 0.76 | HTR2C (0.64) | HTR2CPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107605-A1 | CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2010-09-23 | — | — | WO | disclosed |