SCHEMBL13192076

SCHEMBL13192076

COC(=O)NC1(C)CC(NC(=O)O)CC(C)(C)C1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9357874 0.90 TSHR (0.57) TSHRALDH1A1
SCHEMBL14548992 0.88 TSHR (0.55) TSHRALDH1A1
SCHEMBL25700439 0.84 TSHR (0.45) TSHR
SCHEMBL13171491 0.82 TSHR (0.53) TSHR
SCHEMBL13966178 0.80 TSHR (0.39) TSHRALDH1A1
SCHEMBL14679460 0.79 TSHR (0.45) TSHRALDH1A1
SCHEMBL13171371 0.77 TSHR (0.54) TSHR
SCHEMBL25468755 0.76 TSHR (0.47) TSHR
SCHEMBL26299056 0.76 TSHR (0.47) TSHR
SCHEMBL12942559 0.76 TSHR (0.68) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8444899-B2 Methods and materials for fabricating microfluidic devices THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-05-21 US disclosed
US-20120256354-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-10-11 US disclosed