Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012303 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL7853583 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL8626292 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL2760851 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL8028639 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL8630360 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL8629278 | 0.85 | ZDHHC7 (0.56) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL7199656 | 0.83 | ZDHHC7 (0.54) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL1484420 | 0.83 | ZDHHC7 (0.54) | CA2CA1RECQLZDHHC7CA14 | |
| SCHEMBL69695 | 0.83 | ZDHHC7 (0.54) | CA2CA1RECQLZDHHC7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138749-A1 | METHODS FOR DECREASING OCULAR TOXICITY OF ANTIBODY DRUG CONJUGATES | IMMUNOGEN, INC. (US) | 2012-10-11 | — | — | WO | disclosed |