Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29371674 | 1.00 | TLR2 (0.45) | TLR2TPSAB1KMT2ASIRT5PTPN1 | |
| SCHEMBL13311052 | 1.00 | TLR2 (0.45) | TLR2TPSAB1KMT2ASIRT5PTPN1 | |
| SCHEMBL23477323 | 0.94 | TLR2 (0.45) | TLR2KMT2APTPN1SIRT1SIRT2 | |
| SCHEMBL16450347 | 0.94 | PTPN1 (0.48) | KMT2ASIRT5PTPN1 | |
| SCHEMBL30895476 | 0.93 | PTPN1 (0.51) | TLR2SIRT5PTPN1 | |
| SCHEMBL31681555 | 0.92 | KMT2A (0.43) | TLR2TPSAB1KMT2ASIRT5PTPN1 | |
| SCHEMBL25148139 | 0.92 | KMT2A (0.43) | TLR2TPSAB1KMT2ASIRT5PTPN1 | |
| SCHEMBL29649468 | 0.92 | TLR2 (0.45) | TLR2TPSAB1KMT2ASIRT5PTPN1 | |
| SCHEMBL26015800 | 0.92 | TLR2 (0.45) | TLR2TPSAB1KMT2ASIRT5PTPN1 | |
| SCHEMBL17813684 | 0.92 | TLR2 (0.45) | TLR2TPSAB1KMT2ASIRT5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724426-B2 | Agents, uses and methods | AFFINICON APS (DK) | 2017-08-08 | — | — | US | disclosed |
| US-20120258107-A1 | Agents, Uses and Methods | CYTOGUIDE APS (DK) | 2012-10-11 | — | — | US | disclosed |
| US-20100092496-A1 | CHEMICAL LINKERS AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2010-04-15 | — | — | US | disclosed |
| US-7691962-B2 | Chemical linkers and conjugates thereof | MEDAREX, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080279868-A1 | Antibody-Drug Conjugates and Methods of Use | MEDAREX, INC. (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279868-A1 | Antibody-Drug Conjugates and Methods of Use | CD47, ANTXR2, CD2BP2 | TLR2 3383/4885TPSAB1 2027/4885KMT2A 2408/4885 |
| US-20100092496-A1 | CHEMICAL LINKERS AND CONJUGATES THEREOF | CLSPN, CD74, ANTXR2 | TLR2 2508/4885TPSAB1 3862/4885KMT2A 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.