Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13197822 | 0.88 | EPHX2 (0.43) | SMN1; SMN2FPR2IGF1REPHX2PPARA | |
| SCHEMBL13197831 | 0.86 | EPHX2 (0.42) | FPR2IGF1REPHX2ALDH1A1AHR | |
| SCHEMBL2567978 | 0.86 | EPHX2 (0.53) | SMN1; SMN2FPR2TP53IGF1REPHX2 | |
| SCHEMBL13197853 | 0.85 | EPHX2 (0.43) | EPHX2ALDH1A1AHRHPGD | |
| SCHEMBL13197833 | 0.85 | EPHX2 (0.48) | SMN1; SMN2FPR2TP53IGF1REPHX2 | |
| SCHEMBL13197846 | 0.85 | EPHX2 (0.42) | FPR2IGF1REPHX2ALDH1A1AHR | |
| SCHEMBL13197817 | 0.85 | EPHX2 (0.44) | EPHX2ALDH1A1AHRHPGD | |
| SCHEMBL13197836 | 0.84 | IGF1R (0.47) | SMN1; SMN2FPR2TP53IGF1REPHX2 | |
| SCHEMBL13197832 | 0.82 | EPHX2 (0.54) | SMN1; SMN2IGF1REPHX2PPARALMNA | |
| SCHEMBL13197917 | 0.82 | MCHR1 (0.48) | SMN1; SMN2FPR2TP53IGF1REPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767704-B2 | Antiviral 4-aminocarbonylamino-substituted imidazole compounds | AICURIS GMBH & CO. KG (DE) | 2010-08-03 | — | — | US | disclosed |
| US-7767704-B2 | Antiviral 4-aminocarbonylamino-substituted imidazole compounds | AICURIS GMBH & CO. KG (DE) | 2010-08-03 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | IRF3, EIF2AK2, ZC3HAV1 | SMN1; SMN2 2449/4885FPR2 4423/4885TP53 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.