Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 2/20 | 0.47 |
| ▸ | SELE | P16581 | 2/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963230 | 0.95 | GAA (0.54) | GAAKMT2AMEN1HCAR2LMNA | |
| SCHEMBL13382796 | 0.93 | GAA (0.55) | GAAKMT2AMEN1HCAR2LMNA | |
| SCHEMBL13382784 | 0.89 | GAA (0.48) | GAAKMT2AMEN1HCAR2LMNA | |
| SCHEMBL2741339 | 0.88 | GAA (0.60) | GAAKMT2AMEN1HCAR2LMNA | |
| SCHEMBL14963231 | 0.85 | GAA (0.47) | GAAKMT2AMEN1HCAR2LMNA | |
| SCHEMBL8078098 | 0.82 | GAA (0.67) | GAAKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL20390741 | 0.79 | GAA (0.70) | GAAKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7735505 | 0.79 | GAA (0.62) | GAAKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL13382785 | 0.79 | GAA (0.49) | GAAKMT2AMEN1HCAR2LMNA | |
| SCHEMBL11702602 | 0.78 | GAA (0.72) | GAAKMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767853-B2 | Antioxidants and methods of making and using the same | POLNOX CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |