Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.52 |
| ▸ | FAP | Q12884 | 5/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2965593 | 0.93 | DPP4 (0.46) | DPP4FAPCHRM1MEN1MAPT | |
| SCHEMBL13200086 | 0.90 | DPP4 (0.53) | DPP4FAPCHRM1MEN1MAPT | |
| SCHEMBL13200079 | 0.90 | DPP4 (0.61) | DPP4FAPCHRM1MAPTALDH1A1 | |
| SCHEMBL13200422 | 0.84 | DPP4 (0.56) | DPP4FAPCHRM1DPP9HTR3A | |
| Trifluoroacetic Acid SCHEMBL2961122 | 0.84 | DPP4 (0.55) | DPP4FAPCHRM1DPP9 | |
| Trifluoroacetic Acid SCHEMBL2967789 | 0.84 | DPP4 (0.49) | DPP4FAPCHRM1MEN1MAPT | |
| SCHEMBL13200101 | 0.82 | DPP4 (0.52) | DPP4FAPCHRM1DPP9 | |
| SCHEMBL13200368 | 0.81 | DPP4 (0.53) | DPP4FAPCHRM1DPP9HTR3A | |
| SCHEMBL13200096 | 0.81 | DPP4 (0.59) | DPP4FAPCHRM1MAPTLMNA | |
| SCHEMBL13200047 | 0.81 | DPP4 (0.64) | DPP4FAPCHRM1DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772226-B2 | Condensed imidazole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | DPP4, HDAC1, DPP7 | DPP4 1/4885FAP 3205/4885CHRM1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.