Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.60 |
| ▸ | FAP | Q12884 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2965680 | 0.94 | DPP4 (0.57) | DPP4CHRM1FAP | |
| SCHEMBL13217742 | 0.90 | DPP4 (0.47) | DPP4CHRM1 | |
| SCHEMBL2965678 | 0.87 | DPP4 (0.66) | DPP4CHRM1FAP | |
| SCHEMBL13200816 | 0.85 | DPP4 (0.58) | DPP4CHRM1FAP | |
| SCHEMBL5354261 | 0.85 | DPP4 (0.61) | DPP4CHRM1FAP | |
| SCHEMBL13200817 | 0.84 | DPP4 (0.58) | DPP4CHRM1FAP | |
| SCHEMBL13200812 | 0.83 | DPP4 (0.51) | DPP4CHRM1FAP | |
| SCHEMBL13200818 | 0.83 | DPP4 (0.59) | DPP4CHRM1FAP | |
| SCHEMBL13200755 | 0.83 | DPP4 (0.69) | DPP4CHRM1FAP | |
| SCHEMBL5360460 | 0.82 | DPP4 (0.65) | DPP4CHRM1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772226-B2 | Condensed imidazole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | DPP4, HDAC1, DPP7 | DPP4 1/4885CHRM1 43/4885FAP 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.