Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61605 | 1.00 | MAOB (0.64) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13201653 | 0.93 | MAOB (0.55) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL62106 | 0.93 | MAOB (0.55) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29169442 | 0.90 | MEN1 (0.65) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29169476 | 0.86 | MEN1 (0.69) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28386211 | 0.86 | MEN1 (0.69) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29169445 | 0.86 | MEN1 (0.69) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30782952 | 0.86 | MEN1 (0.69) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17026676 | 0.85 | MIF (0.62) | MAOBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL26987435 | 0.85 | MIF (0.62) | MAOBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772047-B2 | Dyes having ratiometric fluorescence response for detecting metabolites | BECTON, DICKINSON AND COMPANY (US) | 2014-07-08 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| US-20080311675-A1 | DYES HAVING RATIOMETRIC FLUORESCENCE RESPONSE FOR DETECTING METABOLITES | BECTON, DICKINSON AND COMPANY (US) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | MAOB 4281/4885MAPT 2743/4885MEN1 4815/4885 |
| US-20080311675-A1 | DYES HAVING RATIOMETRIC FLUORESCENCE RESPONSE FOR DETECTING METABOLITES | FABP1, FABP5, FABP7 | MAOB 1874/4885MAPT 2137/4885MEN1 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.