Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SCP2 | P22307 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23373810 | 0.84 | MEN1 (0.66) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL62448 | 0.83 | MEN1 (0.69) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL62437 | 0.81 | MEN1 (0.59) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL8858355 | 0.77 | NPC1 (0.76) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL13182571 | 0.76 | MEN1 (0.60) | MEN1NPC1POLBRAB9AKMT2A | |
| Nile Red SCHEMBL49047 | 0.74 | MEN1 (1.00) | MEN1NPC1POLBRAB9AKMT2A | |
| Nile Red SCHEMBL29373685 | 0.74 | MEN1 (1.00) | MEN1NPC1POLBRAB9AKMT2A | |
| Nile Red SCHEMBL28703996 | 0.74 | MEN1 (0.93) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL31722939 | 0.72 | NPC1 (0.74) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL14986327 | 0.72 | NPC1 (0.74) | MEN1NPC1POLBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |