Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD2 | Q9Y5L3 | 3/20 | 0.61 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210938 | 0.92 | ENTPD2 (0.52) | ENTPD2ENTPD1ADORA3ADORA2AADORA1 | |
| SCHEMBL13210940 | 0.91 | ENTPD2 (0.56) | ENTPD2ENTPD1ADORA3ADORA2AADORA1 | |
| SCHEMBL13210931 | 0.90 | ENTPD2 (0.63) | ENTPD2ENTPD1P2RY14 | |
| SCHEMBL13210942 | 0.87 | ENTPD2 (0.46) | ENTPD2ENTPD1ADORA3P2RY14 | |
| SCHEMBL13210937 | 0.86 | ENTPD2 (0.66) | ENTPD2ENTPD1ADORA3ADORA1ADORA2B | |
| SCHEMBL13210929 | 0.80 | ENTPD1 (0.67) | ENTPD2ENTPD1ADORA3ADORA1ADORA2B | |
| SCHEMBL13210936 | 0.79 | ENTPD2 (0.49) | ENTPD2ENTPD1P2RY14 | |
| SCHEMBL13210935 | 0.79 | ENTPD2 (0.41) | ENTPD2ENTPD1ADORA3ADORA2AADORA1 | |
| SCHEMBL13210957 | 0.77 | ENTPD2 (0.51) | ENTPD2ENTPD1ADORA3ADORA1ADORA2B | |
| SCHEMBL13210978 | 0.76 | ENTPD2 (1.00) | ENTPD2ENTPD1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | NT5E, NT5C2, ENTPD1 | ENTPD2 10/4885ENTPD1 3/4885ADORA3 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.