Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13215068 | 0.96 | HRH3 (0.36) | HRH3S1PR3F10PRSS1PRSS2 | |
| SCHEMBL12995273 | 0.91 | HRH3 (0.36) | HRH3S1PR3 | |
| SCHEMBL13215304 | 0.90 | KMT2A (0.37) | SMN1; SMN2 | |
| SCHEMBL12995100 | 0.87 | HRH3 (0.37) | HRH3S1PR3NPY1RSMN1; SMN2 | |
| SCHEMBL14467817 | 0.86 | NPC1 (0.40) | HRH3 | |
| SCHEMBL12995221 | 0.86 | HRH3 (0.39) | HRH3S1PR3 | |
| SCHEMBL12995260 | 0.86 | HRH3 (0.38) | HRH3S1PR3 | |
| SCHEMBL12995218 | 0.85 | S1PR3 (0.38) | HRH3S1PR3 | |
| SCHEMBL12995225 | 0.85 | HRH3 (0.37) | HRH3S1PR3 | |
| SCHEMBL13053211 | 0.85 | HRH3 (0.37) | HRH3S1PR3F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |