Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199769 | 0.76 | CNR1 (0.33) | POLB | |
| SCHEMBL4622057 | 0.71 | TSHR (0.33) | TSHRCYP2C19 | |
| SCHEMBL3126654 | 0.70 | POLB (0.52) | TSHRCYP2C19LMNAPOLB | |
| SCHEMBL9257470 | 0.70 | — | — | |
| SCHEMBL24133231 | 0.69 | TSHR (0.37) | TSHRCYP2C19LMNAPOLB | |
| SCHEMBL16553553 | 0.68 | TSHR (0.38) | TSHRCYP2C19LMNAPOLB | |
| SCHEMBL6239127 | 0.67 | TSHR (0.36) | TSHRCYP2C19LMNAPOLB | |
| SCHEMBL1362082 | 0.67 | TSHR (0.36) | TSHRCYP2C19LMNAPOLB | |
| SCHEMBL11769603 | 0.65 | AR (0.35) | TSHRPOLB | |
| SCHEMBL15026088 | 0.64 | CYP2C19 (0.46) | TSHRCYP2C19LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772433-B2 | SARMS and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20080057068-A1 | SARMS and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057068-A1 | SARMS and method of use thereof | SARM1, CKMT1A; CKMT1B, TNNI3 | TSHR 2773/4885CYP2C19 4452/4885LMNA 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.