Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13200342 | 0.88 | DPP4 (0.53) | DPP4KCNH2 | |
| SCHEMBL13217116 | 0.83 | SMN1; SMN2 (0.42) | DPP4PIM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL13217360 | 0.83 | DPP4 (0.43) | DPP4PIM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL13217861 | 0.83 | NPSR1 (0.45) | DPP4PIM1L3MBTL1ALDH1A1POLB | |
| Trifluoroacetic Acid SCHEMBL2958386 | 0.82 | DPP4 (0.47) | DPP4KCNH2 | |
| SCHEMBL13217557 | 0.82 | DPP4 (0.39) | DPP4PIM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL13217549 | 0.82 | PIM1 (0.39) | DPP4PIM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL13217391 | 0.82 | DPP4 (0.42) | DPP4PIM1L3MBTL1ALDH1A1POLB | |
| SCHEMBL13217101 | 0.81 | DPP4 (0.45) | DPP4PIM1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13217349 | 0.81 | PIM1 (0.46) | DPP4PIM1L3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772226-B2 | Condensed imidazole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018331-A1 | CONDENSED IMIDAZOLE DERIVATIVES | DPP4, HDAC1, DPP7 | DPP4 1/4885PIM1 1065/4885L3MBTL1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.