Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203598 | 0.88 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13203490 | 0.88 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13221300 | 0.88 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13203579 | 0.88 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13203486 | 0.86 | KDM4E (0.54) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13203574 | 0.85 | HDAC6 (0.57) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13221301 | 0.84 | ESR1 (0.59) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13203569 | 0.84 | HDAC6 (0.51) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13203580 | 0.83 | HDAC6 (0.50) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL2964659 | 0.83 | HDAC6 (0.60) | HDAC6HDAC3HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777051-B2 | Asymmetric benzimidazoles and related compounds as potassium channel modulators | ICAGEN, INC. (US) | 2010-08-17 | — | — | US | disclosed |