SCHEMBL13229809

SCHEMBL13229809

Cc1sc(C)c(C(=O)NC2(c3ccc(C(=O)O)cc3)CC2)c1Cc1ccc(CF)cc1

nearest known ligand 0.80

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.80
PTGER2 P43116 6/20 0.80
PTGDR Q13258 2/20 0.38
TBXA2R P21731 1/20 0.38
PTGER1 P34995 1/20 0.38
PTGFR P43088 1/20 0.38
PTGER3 P43115 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2351863 0.89 PTGER4 (1.00) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL4085052 0.88 PTGER4 (0.98) PTGER4PTGER2PTGDRTBXA2RPTGER1
Diethylamine SCHEMBL3019803 0.85 PTGER4 (0.91) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL13655932 0.85 PTGER4 (0.69) PTGER4PTGER2
SCHEMBL2352729 0.82 PTGER4 (1.00) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL4100421 0.81 PTGER4 (0.98) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL13210500 0.81 PTGER4 (0.86) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL4085048 0.80 PTGER4 (0.83) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL4090366 0.80 PTGER4 (0.83) PTGER4PTGER2PTGDRTBXA2RPTGER1
SCHEMBL13230152 0.79 PTGER4 (0.62) PTGER4PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100204487-A1 PROCESS FOR MAKING THIOPHENE CARBOXAMIDE DERIVATIVES DAVIES IAN 2010-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204487-A1 PROCESS FOR MAKING THIOPHENE CARBOXAMIDE DERIVATIVES PTGER4, P2RY4, PTGES2 PTGER4 1/4885PTGER2 7/4885PTGDR 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.