⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232234 | 1.00 | — | — | |
| SCHEMBL2379257 | 0.80 | — | — | |
| SCHEMBL17946144 | 0.80 | — | — | |
| SCHEMBL11463019 | 0.78 | — | — | |
| SCHEMBL11479479 | 0.78 | — | — | |
| SCHEMBL11288962 | 0.78 | — | — | |
| SCHEMBL4330615 | 0.77 | CHRM2 (0.49) | — | |
| SCHEMBL8282939 | 0.75 | CHRM2 (0.60) | — | |
| SCHEMBL4338414 | 0.75 | CHRM2 (0.47) | — | |
| SCHEMBL5331770 | 0.75 | CHRM2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362054-B2 | Therapeutic substituted lactams | ALLERGAN, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20100168189-A1 | THERAPEUTIC SUBSTITUTED LACTAMS | ALLERGAN, INC. | 2010-07-01 | — | — | US | disclosed |