⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13238832 | 0.93 | — | — | |
| SCHEMBL13239082 | 0.90 | — | — | |
| SCHEMBL13237981 | 0.89 | — | — | |
| SCHEMBL13409213 | 0.89 | — | — | |
| SCHEMBL13409138 | 0.86 | — | — | |
| SCHEMBL13239311 | 0.86 | — | — | |
| SCHEMBL13239083 | 0.85 | — | — | |
| SCHEMBL13238007 | 0.84 | — | — | |
| SCHEMBL13237991 | 0.84 | KDM4E (0.31) | — | |
| SCHEMBL13238006 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357689-B2 | Substituted arylsulfonylaminomethylphosphonic acid derivatives, their preparation and their use in the treatment of type I and II diabetes mellitus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20100210594-A1 | SUBSTITUTED ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF TYPE I AND II DIABETES MELLITUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-19 | — | — | US | disclosed |