Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783385 | 0.90 | KMT2A (0.56) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL19203449 | 0.90 | KMT2A (0.56) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL13243816 | 0.79 | DPP7 (0.52) | MEN1KMT2AKCNH2L3MBTL1MAPT | |
| SCHEMBL11015731 | 0.79 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL21258291 | 0.79 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL14202766 | 0.79 | NPC1 (0.51) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL3046145 | 0.78 | KMT2A (0.48) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL17559610 | 0.78 | ATM (0.52) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL17559609 | 0.78 | ATM (0.52) | MEN1KMT2ANPC1RAB9AADRA2B | |
| SCHEMBL19521035 | 0.77 | KMT2A (0.46) | MEN1KMT2ANPC1RAB9AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772190-B2 | Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same | BAYER ANIMAL HEALTH GMBH (DE) | 2010-08-10 | — | — | US | disclosed |