SCHEMBL1324474

SCHEMBL1324474

Cc1nn(C)c(O)c1C(=O)c1ccc(Cl)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
MEN1 O00255 4/20 0.52
MAPT P10636 4/20 0.52
HTT P42858 2/20 0.52
NR2F2 P24468 1/20 0.52
HSD17B10 Q99714 1/20 0.48
POLB P06746 3/20 0.45
LMNA P02545 2/20 0.45
CYP2C9 P11712 1/20 0.45
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
SRD5A2 P31213 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10752306 0.99 KMT2A (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10755585 0.99 KMT2A (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
Hydrochloric Acid SCHEMBL10754962 0.99 SMN1; SMN2 (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10752411 0.99 SMN1; SMN2 (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10755257 0.99 KMT2A (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10754395 0.99 KMT2A (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10751457 0.99 KMT2A (0.51) KMT2ASMN1; SMN2MEN1MAPTHTT
Isopropylamine SCHEMBL10754516 0.94 KMT2A (0.47) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10751550 0.89 MAPT (0.43) KMT2ASMN1; SMN2MEN1MAPTHTT
SCHEMBL10751427 0.87 KMT2A (0.53) KMT2ASMN1; SMN2MEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0071833-B1 PROCESS FOR PRODUCING 4-BENZOYLPYRAZOLES ISHIHARA SANGYO KAISHA, LTD. (JP) 1987-02-04 EP claimed
US-4508910-A Herbicidal 4-benzoyl-5-hydroxy-pyrazales SANKYO COMPANY LTD. (JP) 1985-04-02 US claimed
US-4415739-A Process for producing 4-benzoylpyrazoles ISHIHARA SANGYO KAISHA LTD. (JP) 1983-11-15 US claimed
EP-0071833-A1 Process for producing 4-benzoylpyrazoles ISHIHARA SANGYO KAISHA, LTD. (JP) 1983-02-16 EP claimed
EP-0067981-A2 Pyrazole derivatives, process for their preparation and their herbicidal application NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1982-12-29 EP claimed
US-4261729-A Herbicidal compositions and pyrazole derivatives SANKYO COMPANY LIMITED (JP) 1981-04-14 US claimed
US-4063925-A Herbicidal compositions SANKYO COMPANY LIMITED (JA) 1977-12-20 US claimed
JP-57167971-A None JP disclosed
JP-60016986-A None JP disclosed
JP-55031016-A None JP disclosed
JP-55094368-A None JP disclosed
JP-55160765-A None JP disclosed
JP-56147772-A None JP disclosed
US-4146726-A HERBICIDES SANKYO COMPANY LIMITED (JP) 1979-03-27 US disclosed
US-4070536-A Process for the preparation of 4-benzoylpyrazole derivatives SANKYO COMPANY LIMITED (JA) 1978-01-24 US disclosed
US-4063925-A Herbicidal compositions SANKYO COMPANY LIMITED (JA) 1977-12-20 US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 US disclosed
JP-S05547602-A 0001-01-01 JP disclosed
JP-S05533455-A 0001-01-01 JP disclosed
JP-S0616986-A 0001-01-01 JP disclosed