⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Peroxynitrite SCHEMBL6851573 | 0.91 | — | — | |
| Peroxynitrite SCHEMBL15117 | 0.91 | — | — | |
| Peroxynitrite SCHEMBL28447690 | 0.86 | — | — | |
| Peroxynitrite SCHEMBL14964652 | 0.86 | — | — | |
| Peroxynitrite SCHEMBL28863409 | 0.86 | — | — | |
| Peroxynitrite SCHEMBL30148125 | 0.86 | — | — | |
| Peroxynitrite SCHEMBL17180226 | 0.86 | — | — | |
| Peroxynitrite SCHEMBL28300144 | 0.82 | — | — | |
| Peroxynitrite SCHEMBL27699043 | 0.82 | — | — | |
| Bicarbonate SCHEMBL15412927 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10058419-B2 | Oxidation resistant bioprosthetic tissues and preparation thereof | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2018-08-28 | — | — | US | disclosed |
| US-20140288641-A1 | OXIDATION RESISTANT BIOPROSTHETIC TISSUES AND PREPARATION THEREOF | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2014-09-25 | — | — | US | disclosed |
| US-8063101-B2 | Carotenoid analogs and derivatives for the prevention of platelet aggregation | CARDAX PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-8058256-B2 | Polymeric carrier for delivery of small interfering RNA | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110112169-A1 | RNAi-BASED THERAPEUTICS FOR ALLERGIC RHINITIS AND ASTHMA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-12 | — | — | US | disclosed |
| US-20100204297-A1 | INFLUENZA THERAPEUTIC | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-08-12 | — | — | US | disclosed |
| US-7740880-B2 | Polymeric carrier for delivery of small interfering RNA | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-20100130722-A1 | POLYMERIC CARRIER FOR DELIVERY OF SMALL INTERFERING RNA | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-05-27 | — | — | US | disclosed |
| US-20090124574-A1 | Carotenoid analogs and derivatives for the prevention of platelet aggregation | CARDAX PHARMA, INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124567-A1 | Influenza Therapeutic | CHEN JIANZHU | 2009-05-14 | — | — | US | disclosed |
| US-20040242518-A1 | Influenza therapeutic | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-12-02 | — | — | US | disclosed |
| EP-0998577-B1 | CONJUGATES OF TRANSPORTER PEPTIDES AND NUCLEIC ACID ANALOGS, AND THEIR USE | PERSEPTIVE BIOSYSTEMS INC (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040147027-A1 | Complex for facilitating delivery of dsRNA into a cell and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-07-29 | — | — | US | disclosed |
| WO-2004029213-A2 | COMPOSITIONS AND METHODS FOR DELIVERY OF SHORT INTERFERING RNA AND SHORT HAIRPIN RNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-04-08 | — | — | WO | disclosed |
| WO-2004028471-A2 | INFLUENZA THERAPEUTIC | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-04-08 | — | — | WO | disclosed |
| WO-2003004606-A2 | ANTISENSE OLIGONUCLEOTIDES AND RELATED METHODS FOR REGULATING CELL DEATH | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-01-16 | — | — | WO | disclosed |
| EP-0998577-A1 | CONJUGATES OF TRANSPORTER PEPTIDES AND NUCLEIC ACID ANALOGS, AND THEIR USE | PERSEPTIVE BIOSYSTEMS, INC. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6025140-A | NUCLEIC ACID ANALOG CONJUGATED TO A PEPTIDE WITH A SPECIFIC AMINO ACID SEQUENCE BY A LABILE BOND; ANALOG TARGETS A SPECIFIC INTRACELLULAR POLYNUCLEOTIDE FOR ANTISENSE THERAPY | PERSEPTIVE BIOSYSTEMS, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| WO-1999018958-A1 | BATHOCUPROINE TREATMENT OF NEUROLOGIC DISEASE | UAB RESEARCH FOUNDATION (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999005302-A1 | CONJUGATES OF TRANSPORTER PEPTIDES AND NUCLEIC ACID ANALOGS, AND THEIR USE | THE PERKIN-ELMER CORPORATION (US) | 1999-02-04 | — | — | WO | disclosed |