SCHEMBL132494

SCHEMBL132494

c1ccc(C2=C(c3ccccc3)c3ccccc3C2)cc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 0.59
ESR1 P03372 6/20 0.59
PTGS2 P35354 3/20 0.54
PTGS1 P23219 1/20 0.54
CFTR P13569 1/20 0.41
GOPC Q9HD26 1/20 0.41
MAOA P21397 1/20 0.41
KMT2A Q03164 1/20 0.41
KDR P35968 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28811814 0.89 ESR2 (0.56) ESR2ESR1PTGS2PTGS1KMT2A
SCHEMBL28812014 0.85 ESR2 (0.59) ESR2ESR1PTGS2PTGS1
SCHEMBL15679223 0.85 ESR1 (0.55) ESR2ESR1PTGS2PTGS1KMT2A
SCHEMBL2824657 0.81 CES1 (0.45) ESR2ESR1PTGS2PTGS1KMT2A
SCHEMBL15679214 0.79 ESR1 (0.47) ESR2ESR1PTGS2KMT2A
SCHEMBL22635759 0.77 ESR2 (0.46) ESR2ESR1PTGS2PTGS1CFTR
SCHEMBL22635774 0.77 ESR1 (0.50) ESR2ESR1PTGS2PTGS1CFTR
SCHEMBL19019874 0.77 CYP17A1 (0.47) ESR2ESR1PTGS2CFTRGOPC
SCHEMBL27293851 0.77 KDR (0.42) ESR2ESR1PTGS2PTGS1CFTR
SCHEMBL31608569 0.77 CYP17A1 (0.47) ESR2ESR1PTGS2CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2859069-B1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2020-10-14 EP claimed
EP-1521125-B1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH CO LTD (JP) 2012-03-07 EP claimed
US-7556902-B2 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2009-07-07 US claimed
US-7452640-B2 Electrophotographic photoconductor for liquid development, image forming apparatus having the same, and image forming method RICOH COMPANY, LTD. (JP) 2008-11-18 US claimed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US claimed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US claimed
US-20060046169-A1 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2006-03-02 US claimed
EP-1063264-B1 Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus RICOH KK (JP) 2006-03-01 EP claimed
US-20060024597-A1 Electrophotographic photoconductor for liquid development, image forming apparatus having the same, and image forming method RICOH COMPANY, LTD. (JP) 2006-02-02 US claimed
US-20050266331-A1 Electrophotographic photoconductor, electrophotography, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH COMPANY, LTD. (JP) 2005-12-01 US claimed
US-20050112487-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same SHOSHI MASAYUKI (JP) 2005-05-26 US claimed
EP-1521125-A1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound Ricoh Company (JP) 2005-04-06 EP claimed
US-6849367-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2005-02-01 US claimed
US-20030190540-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2003-10-09 US claimed
US-6544701-B2 Crystalline reaction product having charge generating properties of a phenylenebis(dicyanopyrazine) and a phthalonitrile or a diiminoisoindole which may be metallized RICOH COMPANY, LTD. (JP) 2003-04-08 US claimed
US-20030013028-A1 Reaction product, process for the production thereof, electrophotographic photoconductor using the reaction product, electrophotographic apparatus using the photoconductor, and process cartridge for electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2003-01-16 US claimed
EP-1063264-A2 Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus Ricoh Company, Ltd. (JP) 2000-12-27 EP claimed
JP-7333874-A None JP disclosed
US-4075227-A NONSTEROIDAL ELI LILLY AND COMPANY (US) 1978-02-21 US disclosed
US-4017546-A AROYL PHENYL INDENES AND AROYL PHENYL NAPHTHALENES ELI LILLY AND COMPANY (US) 1977-04-12 US disclosed