SCHEMBL1325484

SCHEMBL1325484

C[SiH](C)CCC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15276136 0.73
SCHEMBL7755377 0.73
SCHEMBL2104676 0.69
SCHEMBL1325042 0.69
SCHEMBL5005257 0.69
SCHEMBL17024468 0.69
SCHEMBL15184967 0.67 TSHR (0.35)
SCHEMBL3835667 0.67 TSHR (0.33)
SCHEMBL4770427 0.67
SCHEMBL231464 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693314-B1 Chromatography using silicon dioxide based adsorbents. UETIKON CHEMIE AG (CH) 2001-09-26 EP claimed
EP-4519331-A1 SUBSTITUTED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2025-03-12 EP disclosed
WO-2023215693-A1 SUBSTITUTED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-11-09 WO disclosed
US-8987358-B2 Compound including organopolysiloxane or silsesquioxane skeleton having isocyanuric skeleton, epoxy group and SiH group, thermosetting resin composition containing the compound as adhesion-imparting agent, hardened material and sealing agent for optical semiconductor JNC CORPORATION (JP) 2015-03-24 US disclosed
US-20140148536-A1 COMPOUND INCLUDING ORGANOPOLYSILOXANE OR SILSESQUIOXANE SKELETON HAVING ISOCYANURIC SKELETON, EPOXY GROUP AND SIH GROUP, THERMOSETTING RESIN COMPOSITION CONTAINING THE COMPOUND AS ADHESION-IMPARTING AGENT, HARDENED MATERIAL AND SEALING AGENT FOR OPTICAL SEMICONDUCTOR JNC CORPORATION (JP) 2014-05-29 US disclosed
US-8058261-B2 3′-ethynylcytidine derivative TAIHO PHARMACEUTICAL CO., LTD. (JP) 2011-11-15 US disclosed
EP-2045258-B1 3'-ETHYNYLCYTIDINE DERIVATIVE TAIHO PHARMACEUTICAL CO LTD (JP) 2011-09-21 EP disclosed
US-7825103-B2 5'-O-triisopropylsilyl-2'-cyano-2'-deoxy-1- beta -D-arabinofuranosylcytosine; antitumor agents TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-11-02 US disclosed
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Sasaki, Takuma (JP) 2009-12-10 US disclosed
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 US disclosed
EP-2045258-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2009-04-08 EP disclosed
EP-1845102-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2007-10-17 EP disclosed
US-5762803-A Silicon dioxide based microspheres for rapid chromatographic separation of biomolecules CU CHEMIE UETIKON AG (CH) 1998-06-09 US disclosed
EP-0517262-A1 Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-09 EP disclosed