SCHEMBL1325592

SCHEMBL1325592

C[Si](CCl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324974 0.74
Hydrochloric Acid SCHEMBL28547902 0.70
SCHEMBL467890 0.56
SCHEMBL207623 0.56
Hydrochloric Acid SCHEMBL28904718 0.53
Ethyl Chloride SCHEMBL20021 0.52
Ethyl Chloride SCHEMBL1331853 0.52
Ethyl Chloride SCHEMBL1331994 0.52
SCHEMBL186354 0.52
Methylene Chloride SCHEMBL18604011 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8058261-B2 3′-ethynylcytidine derivative TAIHO PHARMACEUTICAL CO., LTD. (JP) 2011-11-15 US disclosed
EP-2045258-B1 3'-ETHYNYLCYTIDINE DERIVATIVE TAIHO PHARMACEUTICAL CO LTD (JP) 2011-09-21 EP disclosed
US-7825103-B2 5'-O-triisopropylsilyl-2'-cyano-2'-deoxy-1- beta -D-arabinofuranosylcytosine; antitumor agents TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-11-02 US disclosed
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Sasaki, Takuma (JP) 2009-12-10 US disclosed
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 US disclosed
EP-2045258-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2009-04-08 EP disclosed
EP-1845102-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2007-10-17 EP disclosed