Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256370 | 0.93 | HTR2A (0.48) | HTR2APOLQKDM1AHTR2CPDK2 | |
| SCHEMBL30228395 | 0.88 | HTR2C (0.56) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4890973 | 0.87 | HTR2C (0.57) | HTR2AHTR2C | |
| SCHEMBL18162314 | 0.85 | POLQ (0.47) | HTR2APOLQKDM1AHTR2CPDK2 | |
| SCHEMBL3434595 | 0.85 | POLQ (0.47) | HTR2APOLQKDM1AHTR2CPDK2 | |
| SCHEMBL18162311 | 0.84 | POLQ (0.44) | HTR2APOLQHTR2CPDK2NOTUM | |
| SCHEMBL26020142 | 0.82 | SSTR4 (0.35) | HTR2AHTR2CPDK2ESR2PDE2A | |
| SCHEMBL26020163 | 0.79 | POLQ (0.43) | HTR2APOLQKDM1AHTR2CPDK2 | |
| SCHEMBL13002296 | 0.79 | KDM1A (0.53) | HTR2APOLQKDM1AESR2PDE2A | |
| SCHEMBL13838866 | 0.78 | KDM1A (0.61) | HTR2APOLQKDM1AHTR2CPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803210-A | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | claimed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| EP-3577115-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-02 | — | — | EP | disclosed |
| CN-102803210-A | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| WO-2010088574-A1 | AZABENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |