Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257323 | 0.90 | PIK3CA (1.00) | PIK3CA | |
| SCHEMBL13257334 | 0.89 | PIK3CA (1.00) | PIK3CA | |
| SCHEMBL13257350 | 0.89 | PIK3CA (0.68) | PIK3CA | |
| SCHEMBL13258327 | 0.87 | PIK3CA (0.78) | PIK3CA | |
| SCHEMBL13257542 | 0.86 | PIK3CA (0.77) | PIK3CA | |
| SCHEMBL13257327 | 0.86 | PIK3CA (1.00) | PIK3CA | |
| SCHEMBL16500525 | 0.86 | PIK3CA (0.77) | PIK3CA | |
| SCHEMBL13257510 | 0.84 | PIK3CA (0.84) | PIK3CA | |
| SCHEMBL13257364 | 0.83 | PIK3CA (0.79) | PIK3CA | |
| SCHEMBL13258255 | 0.82 | PIK3CA (0.77) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091996-A1 | 2-MORPHOLINO-PYRIDO[3,2-D]PYRIMIDINES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |