SCHEMBL13257572 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK14	Q16539	11/20	0.44

▸	GSK3B	P49841	7/20	0.44

▸	PIK3C3	Q8NEB9	4/20	0.43

▸	MAPK13	O15264	1/20	0.38

▸	MAPK12	P53778	1/20	0.38

▸	KCNH2	Q12809	1/20	0.38

▸	MAPK11	Q15759	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6845070	0.90	KDM4E (0.52)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL6842868	0.90	MAPK14 (0.47)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL6842861	0.90	PIK3C3 (0.45)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL6845075	0.90	PIK3C3 (0.45)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL6842841	0.89	PIK3C3 (0.47)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL6842856	0.89	KDM4E (0.45)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL952377	0.89	MAPK14 (0.48)	MAPK14PIK3C3MAPK13MAPK12MAPK11
SCHEMBL6845099	0.87	PIK3C3 (0.43)	MAPK14GSK3BPIK3C3MAPK13MAPK12
SCHEMBL6845043	0.87	MAPK14 (0.49)	MAPK14GSK3BPIK3C3
SCHEMBL6842845	0.87	MAPK14 (0.43)	MAPK14GSK3BPIK3C3MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010090716-A1	HETEROARYLS AND THEIR USE AS PI3K INHIBITORS	MILLENNIUM PHARMACEUTICALS, INC. (US)	2010-08-12	—	—	WO	disclosed