Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862767 | 0.94 | NR1I2 (0.51) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862668 | 0.93 | NR1I2 (0.61) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862885 | 0.92 | NR1I2 (0.49) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862636 | 0.90 | NR1I2 (0.45) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL13257873 | 0.88 | KCNH2 (0.48) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL13257874 | 0.88 | KCNH2 (0.48) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL862771 | 0.87 | NR1I2 (0.52) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL841218 | 0.87 | KCNH2 (0.51) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL277740 | 0.87 | NR1I2 (0.51) | NR1I2KCNH2SCN9ACYP3A4SCN5A | |
| SCHEMBL278057 | 0.86 | NR1I2 (0.51) | NR1I2KCNH2SCN9ACYP3A4SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093359-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-19 | — | — | WO | disclosed |