Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | ACR | P10323 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007586 | 0.85 | ESR1 (0.51) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL13085851 | 0.84 | ESR1 (0.64) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL13258484 | 0.83 | KMT2A (0.49) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL14579669 | 0.82 | PRSS1 (0.65) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL14007592 | 0.81 | KMT2A (0.47) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL14579677 | 0.81 | KMT2A (0.67) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL17018619 | 0.81 | ESR1 (0.68) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL14007583 | 0.80 | ESR1 (0.47) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL14579726 | 0.80 | MAPT (0.54) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL13341069 | 0.79 | ESR1 (0.53) | ESR1ESR2KMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445079-B2 | Optical film, image display device, diethynylfluorene, and polymer thereof | NITTO DENKO CORPORATION (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8309186-B2 | — | — | 2012-11-13 | — | — | US | disclosed |
| US-20100182693-A1 | OPTICAL FILM, IMAGE DISPLAY DEVICE, DIETHYNYLFLUORENE, AND POLYMER THEREOF | NITTO DENKO CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100182693-A1 | OPTICAL FILM, IMAGE DISPLAY DEVICE, DIETHYNYLFLUORENE, AND POLYMER THEREOF | CDYL, CD79B, CDY1; CDY1B | ESR1 1423/4885ESR2 1573/4885KMT2A 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.